
Cross-protection in opposition to homo and heterologous influenza viruses by way of intranasal administration of an HA chimeric multiepitope nanoparticle vaccine | Journal of Nanobiotechnology
Experimental design The target of this examine is to develop a brand new technology of influenza vaccines which might be secure, environment friendly and virus-independent and that induce cross-protection. We developed ferritin-based nanoparticle vaccines which had been fused with the ectodomain of the influenza HA protein, three sequential repeats of extremely conserved M2e epitopes, and…