
Vibrant NIR-II emissive cyanine dye-loaded lipoprotein-mimicking nanoparticles for fluorescence imaging-guided and focused NIR-II photothermal remedy of subcutaneous glioblastoma | Journal of Nanobiotechnology
Design and synthesis The artificial route towards AIE motif-functionalized NIR-II dyes is illustrated in Scheme S1 and supporting data. Typically, the accessible nucleophilic substitution of the meso-position chlorine in NIR-C12 with the thiol group of mercaptobenzoic acid yielded carboxylic acid-functionalized NIR-C12. The obtained compound NIR-C12-COOH underwent an amidation coupling response between carboxylic acid teams and…