Lewis, L. M., Badkar, A. V., Cirelli, D., Combs, R. & Lerch, T. F. The race to develop the Pfizer–BioNTech COVID-19 vaccine: from the pharmaceutical scientists’ perspective. J. Pharm. Sci. 112, 640–647 (2023). Article CAS PubMed Google Scholar Thorn, C. R. et al. The journey of a lifetime — growth of Pfizer’s COVID-19 vaccine. Curr….
Reviewed by Lexie NookJan 15 2025 Rice College researchers revealed a research within the journal Carbon, demonstrating that carbon nanotube (CNT) fibers could be recycled with out dropping their construction or properties, supporting efforts towards a extra sustainable and round financial system. Carbon nanotube fibers. Picture Credit score: Jeff Fitlow/Rice College This discovering positions CNT fibers as…
Working mannequin displaying wi-fi DBS mediated by ATB NPs to reverse PD. Credit score: Science Advances (2025). DOI: 10.1126/sciadv.ado4927 Parkinson’s illness (PD) is the second commonest neurodegenerative dysfunction, primarily characterised by motor dysfunction. Its pathological hallmark is the irregular aggregation of α-synuclein (α-syn) into insoluble fibrils and Lewy our bodies, resulting in the degeneration and…
How can we be sure that life-saving medication or genetic therapies attain their meant goal cells with out inflicting dangerous unwanted side effects? Researchers at Helmholtz Munich, Ludwig-Maximilians-Universität (LMU) and Technical College Munich (TUM) have taken an vital step to reply this query. They’ve developed a way that, for the primary time, permits the exact…
Non-clinical (non cGMP) sEV manufacturing and enrichment Preclinical sEV batches had been obtained as reported beforehand [20]. Briefly, UC-MSC from three donors in passage 5 had been seeded and expanded in a upkeep medium composed of Dulbecco’s modified Eagle’s medium (DMEM), excessive glucose, supplemented with 1% penicillin/streptomycin resolution (10,000 U/mL and 10,000 μg/mL, respectively), 1% L-glutamine (200 mM)…
Kaiser, J. Personalised tumour vaccines preserve most cancers in examine. Science 356, 122 (2017). Article PubMed CAS Google Scholar Pulendran, B. & Davis, M. M. The science and medication of human immunology. Science 369, eaay4014 (2020). Article PubMed PubMed Central CAS Google Scholar Ci, T. et al. Cryo-shocked most cancers cells for focused drug supply…
In a latest article printed in Scientific Experiences, researchers explored the inexperienced synthesis of zinc oxide nanoparticles (ZnO NPs) utilizing the extract of Padina pavonica, a brown algae. They evaluated their effectiveness in eradicating methylene blue dye from aqueous options. The analysis goals to display the potential of those biogenic nanoparticles as a viable resolution…
Laura Spies appears to be like at one of many COF skinny movies examined within the examine. Credit score: Florian Wolf An interdisciplinary analysis group from LMU, the Technical College of Munich (TUM), and the College of Oxford has employed novel spectroscopic methods to research the diffusion of excited states in covalent natural frameworks (COFs)….
Alloying, the artwork of mixing metals with different components, has lengthy been a cornerstone of supplies science and metallurgy, creating supplies with tailor-made properties. In distinction, dealloying has been identified primarily as a corrosive course of that degrades supplies over time by selectively eradicating components, weakening their construction. Now, researchers on the Max Planck Institute…
Synthesis and characterization of bioactive TPSF materials with ROS-scavenging potential Tpl is a SOD-mimetic agent that may successfully neutralize superoxide anions and oxygen radicals [65]. In the meantime the PBAP unit is ready to stoichiometrically inactivate H2O2 [41]. Thus, we designed a silk-based ROS scavenger, outlined as TPSF, which was concurrently chemically modified with each…