ON–OFF nanopores for optical management of transmembrane ionic communication

ON–OFF nanopores for optical management of transmembrane ionic communication

Bozovic, O., Jankovic, B. & Hamm, P. Utilizing azobenzene photocontrol to set proteins in movement. Nat. Rev. Chem. 6, 112–124 (2022). Article  CAS  PubMed  Google Scholar  Emiliani, V. et al. Optogenetics for gentle management of organic programs. Nat. Rev. Strategies Primers 2, 55 (2022). Article  CAS  PubMed  PubMed Central  Google Scholar  Kramer, R. H., Chambers,…

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Scientists Create the Largest Atomically Skinny Gold Movies to Make Electronics Weightless and Invisible

Scientists Create the Largest Atomically Skinny Gold Movies to Make Electronics Weightless and Invisible

XPANCEO, a deep tech firm creating the subsequent era of computing by means of its first sensible contact lenses, in collaboration with Nobel laureate Konstantin S. Novoselov (College of Manchester, Nationwide College of Singapore), has developed an progressive technique for producing biocompatible, clear, ultrathin gold movies with no space restriction. With superior electrical conductivity, these movies pave the best way…

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Micro organism in polymers create cable-like constructions that develop into dwelling gels

Micro organism in polymers create cable-like constructions that develop into dwelling gels

A 3D rendering captured with a confocal microscope exhibits the event of serpentine “cables” as non-motile E. coli bacterial cells proliferate in a polymeric answer. Scale bars are included. Credit score: Sebastian Gonzalez La Corte et al./Princeton College/Caltech Scientists at Caltech and Princeton College have found that bacterial cells rising in an answer of polymers,…

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New chainmail-like materials might be the way forward for armor

New chainmail-like materials might be the way forward for armor

In a outstanding feat of chemistry, a Northwestern College-led analysis staff has developed the primary two-dimensional (2D) mechanically interlocked materials. Resembling the interlocking hyperlinks in chainmail, the nanoscale materials reveals distinctive flexibility and power. With additional work, it holds promise to be used in high-performance, lightweight physique armor and different makes use of that demand…

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M cells focused H. pylori antigen SAM-FAdE displayed on bacterium-like particles induce protecting immunity | Journal of Nanobiotechnology

M cells focused H. pylori antigen SAM-FAdE displayed on bacterium-like particles induce protecting immunity | Journal of Nanobiotechnology

Strains and mouse Escherichia coli DE3 and L. lactis NZ9000 are maintained on this laboratory. E. coli DE3 was routinely cultured in Luria-Bertani (LB) medium at 37 °C, whereas NZ9000 was amplified and cultured in M17 medium supplemented with 0.5% glucose at 30 °C. H. pylori SS1 was cultured on 90 mm Columbia blood agar plate containing H….

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Chemistry, manufacturing and controls methods for utilizing novel excipients in lipid nanoparticles

Chemistry, manufacturing and controls methods for utilizing novel excipients in lipid nanoparticles

Lewis, L. M., Badkar, A. V., Cirelli, D., Combs, R. & Lerch, T. F. The race to develop the Pfizer–BioNTech COVID-19 vaccine: from the pharmaceutical scientists’ perspective. J. Pharm. Sci. 112, 640–647 (2023). Article  CAS  PubMed  Google Scholar  Thorn, C. R. et al. The journey of a lifetime — growth of Pfizer’s COVID-19 vaccine. Curr….

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Sustainable Future for Carbon Nanotubes

Sustainable Future for Carbon Nanotubes

Reviewed by Lexie NookJan 15 2025 Rice College researchers revealed a research within the journal Carbon, demonstrating that carbon nanotube (CNT) fibers could be recycled with out dropping their construction or properties, supporting efforts towards a extra sustainable and round financial system. Carbon nanotube fibers. Picture Credit score: Jeff Fitlow/Rice College This discovering positions CNT fibers as…

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Nanoparticles restore neurons in Parkinson’s with wi-fi mind stimulation

Nanoparticles restore neurons in Parkinson’s with wi-fi mind stimulation

Working mannequin displaying wi-fi DBS mediated by ATB NPs to reverse PD. Credit score: Science Advances (2025). DOI: 10.1126/sciadv.ado4927 Parkinson’s illness (PD) is the second commonest neurodegenerative dysfunction, primarily characterised by motor dysfunction. Its pathological hallmark is the irregular aggregation of α-synuclein (α-syn) into insoluble fibrils and Lewy our bodies, resulting in the degeneration and…

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New chainmail-like materials might be the way forward for armor

SCP-Nano: A brand new expertise to visualise nanocarriers in cells and tissues

How can we be sure that life-saving medication or genetic therapies attain their meant goal cells with out inflicting dangerous unwanted side effects? Researchers at Helmholtz Munich, Ludwig-Maximilians-Universität (LMU) and Technical College Munich (TUM) have taken an vital step to reply this query. They’ve developed a way that, for the primary time, permits the exact…

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Medical-grade extracellular vesicles derived from umbilical wire mesenchymal stromal cells: preclinical growth and first-in-human intra-articular validation as therapeutics for knee osteoarthritis | Journal of Nanobiotechnology

Medical-grade extracellular vesicles derived from umbilical wire mesenchymal stromal cells: preclinical growth and first-in-human intra-articular validation as therapeutics for knee osteoarthritis | Journal of Nanobiotechnology

Non-clinical (non cGMP) sEV manufacturing and enrichment Preclinical sEV batches had been obtained as reported beforehand [20]. Briefly, UC-MSC from three donors in passage 5 had been seeded and expanded in a upkeep medium composed of Dulbecco’s modified Eagle’s medium (DMEM), excessive glucose, supplemented with 1% penicillin/streptomycin resolution (10,000 U/mL and 10,000 μg/mL, respectively), 1% L-glutamine (200 mM)…

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